The SEMI Startups for Sustainable Semiconductors (S3) program announced 15 startups chosen as finalists for pitching to the industry at SEMICON West 2025 in Phoenix, Arizona. The finalists were chosen from a field of 35 semifinalists after a virtual pitch event over 2 days. Startups were evaluated by the organizing committee on five factors: the sustainability impact on our industry, commercial viability of product, company value proposition, the quality of the pitch and the startup team.The committee, made up of experienced Corporate Venture Capitalists (CVCs) from the global semiconductor industry, initially received 145 submissions in all three categories identified for 2025:Sustainable Semiconductor ManufacturingSustainable Data CenterGen AI for Sustainable DesignNow in its 4th year, the program features strong exposure to semiconductor industry CVCs, through the personal mentoring each startup receives. Mentoring topics are tailored to align with the needs and strategic positioning of the startup business plan, and can range from basic introduction to semiconductor manufacturing, to connections to new funding sources. A full analysis of the program over the past 3 years is available here.The SEMI Startups for Sustainability Semiconductor pitch event will take place at the Sustainability Pavilion Stage on Wednesday, October 8 starting at 1:00 p.m. Program lead John Wei of Applied Ventures will open the session and introduce a fireside chat featuring Dr. Om Nalamasu, CTO of Applied Materials and Chair of Applied Ventures and Dr. Melissa Grupen-Shemansky, CTO of SEMI, and moderated by Saifi Usmani, SEMI Vice President of Sustainability. These executives will discuss the role of startups in semiconductor sustainability, along with a variety of related topics. The finalist pitches are scheduled from 2:00 to 4:40 p.m., with each presenter given a 10-minute time slot.Investors are welcome to attend the session at SEMICON West and to register their interest here to learn more about the 2026 program.2025 S3 FinalistsActasys Inc.Brooklyn, NY, USA Actasys has developed a precision cooling solution designed for thermal bottlenecks in semiconductor-driven systems such as networking cards (NICs), DPUs, switches, and optical transceivers. Instead of cooling entire racks or server rooms ActaJet™ targets localized hotspots at the device level, delivering scalable, high-efficiency airflow through a compact, adaptive, and electronically controlled actuator system. AlixLabs ABLund, Sweden AlixLabs AB is developing a disruptive semiconductor manufacturing technology based on Atomic Layer Pitch Splitting (APS). It enables cost-effective and environmentally sustainable scaling of transistor architectures by doubling pattern density without requiring advanced lithography. The core product includes both the APS process and customized etching equipment that integrates into existing semiconductor fab workflows, reducing complexity, cost, and environmental impact.AllonniaBoston, MA, USA Allonnia delivers on-site PFAS treatment with SAFF® (Surface Active Foam Fractionation), a modular system that uses air to naturally separate long- and short-chain PFAS from water. SAFF concentrates PFAS up to 100,000x, minimizing waste and enabling cost-effective, closed-loop management alongside any destruction technology. This plug-and-play solution helps fabs meet strict regulations while advancing sustainability goals with low OPEX and seamless integration into existing operations.AlsemySeoul, South Korea Alsemy is building an AI-powered platform that bridges Manufacturing Execution Systems (MES) and EDA domains enabling fabless engineers to reflect manufacturing data characteristics in their chip designs, while process engineers can make data-driven decisions to optimize manufacturing processes for maximum chip performance. By connecting these traditionally siloed areas, a feedback loop is created to drive efficiency and innovation across the semiconductor value chain.Arieca IncPittsburgh, PA, USA Arieca's adaptable Liquid Metal Embedded Elastomer (LMEE) technology, which blends liquid metal and polymer, delivers both thermal performance and mechanical reliability. LMEEs are a cost-effective, dispensable emulsion that is compatible with existing high volume manufacturing tools and allows for low pressure spreading and excellent wetting. CuspAICambridge, UK CuspAI is building an engine that combines Gen AI models, virtual twins, and active learning pipelines for simulation to develop sustainable materials solutions that address critical environmental challenges, including, environmentally-friendly etching reagents, specialized sorbents for emissions capture, and novel catalysts for manufacturing waste remediation. The engine has already proven successful in designing metal-organic frameworks (MOFs) for carbon capture and PFAS removal from water.FlexiramicsEnshede, The Netherlands Flexiramics® is a breakthrough flexible, 100% ceramic fiber material designed as a drop-in replacement for glass fiber in PCBs. By enhancing thermal conductivity and reducing signal loss, it enables semiconductor manufacturers to build faster, cooler, and more reliable devices. This translates into higher performance, longer lifetimes, and greater efficiency for next-generation chips and advanced electronic systems.icspiKitchener, ON, Canada icspi has developed the microAFM, a scalable atomic force microscope (AFM) on a 1 mm^2 MEMS scan head, 1,000,000x smaller than conventional AFMs. MicroAFM technology enables parallel arrays of thousands of devices for sub-nanometer metrology and inspection with unprecedented throughput, accelerating time-to-yield and reducing scrap.Mixx Technologies, Inc.San Jose, CA, USA Mixx Technologies is a deep-tech startup building next-generation optical interconnect solutions to deliver non-blocking, energy-efficient data movement. The advanced 3DS platform enables petabit level end-to-end connectivity for AI workloads resulting in sustainable, efficient, and cost-effective scaling. The 3DS platform comprised of the engine, package and system, enables seamless deployment of the optical IO chiplet.Point2 TechnologySan Jose, CA, USA Point2 designs and manufactures mixed-signal interconnect SoCs for terabit data transmission, to overcome the barriers of copper and optical cabling to accelerate AI interconnect in GPU cluster scale-up. e-Tube technology uses an RF Transmitter SoC to convert data from the electrical to the RF domain for transmission over plastic waveguides, with the RF Receiver SoC converting the data from the RF domain back to the electrical domain.PROUDLausanne, Switzerland PROUD's patented diamond-layer technology with the highest heat dissipation capacity ( 1000 W/m.K) of any existing material, deposited on chips, allows a direct upgrade in heat extraction, power output and efficiency.SKYRE, Inc.East Hartford, MA, USA SKYRE, Inc. is a pioneer in hydrogen technology, developing innovative solutions to support a clean energy future. From hydrogen recycling, purification and compression, to sustainable energy systems, we deliver environmentally responsible innovations in high-efficiency, zero-waste hydrogen and carbon transformation technologies—cutting costs, boosting industrial productivity, and reducing environmental impact.SyentaSydney, Australia Syenta has developed LEM - Localized Electrochemical Modelling - a process for depositing metal patterns using a local electrochemical process. The pattern is created on a stamp, which then prints the pattern on the substrate in an additive process.Vionano Innovations IncSt. Paul, MN, USA VioNano Innovations is building a patterning platform to enable advanced feature scaling using self-assembling polymer brush materials. The system enables polymers over 193 nm DUV lithography patterns to double feature density without requiring ALD/CVD or etch steps. The result is a low-energy, high-resolution process for sub-20 nm features using existing infrastructure.XLYNX MaterialsVictoria, BC, Canada XLYNX designs and manufactures a revolutionary family of polymer crosslinkers. These reagents are uniquely able to cure virtually ANY aliphatic polymer, by harnessing high-yielding insertions to carbon-hydrogen bonds. Curing can be triggered thermally (at temperatures as low as 80°C) or photochemically (using either UV or blue light). Heidi Hoffman is Senior Director, Marketing Sustainability at SEMI. Saifi Usmani is VP, Global Industry Sustainability Programs at SEMI.