SMART MedTech Virtual Workshop Series

Biography

Biography

There is an entire field of research dedicated to the chemical analysis of exhaled breath, and the enticing promise of non-invasive medical diagnostics and monitoring. Interestingly, we know that sampling plays a key role in the metabolite content in this complex sample, and biomarker detection and identification in breath may rest on appropriate sampling and analysis protocols. There is also some evidence on how breath chemicals change over time and in response to illness, diet, overall health and exposures. There are also studies that show exogenous drugs measured in breath as well. This talk with highlight our own basic research in this area.

Jennifer's Biography | Sean's Biography

Historically, biomarker discovery efforts have focused on developing sensing strategies for disease diagnosis and prognosis. More recently, the Department of Defense has made a significant investment in wearable sensor and data analytics methods to predict physiologic and cognitive detriment with the goal of improving personnel readiness and augmenting human performance. During this presentation, a broad overview of not only biomarker discovery approaches within Air Force Research Laboratories will be provided, but also future trends and technology gaps limiting fielding of wearable devices, outlining the underpinning for potential external collaborations.

Biography

There are several compounds that interfere with accurate sensing of metabolic analytes in the subcutaneous space, including drugs and endogenous compounds. In addition, when a glucose sensor is exposed to a delivered insulin formulation, there are additional interference issues. Methods of overcoming these threats to accurate sensing will be discussed.

Abstract & Biography