William Jamie Tyler
Co-founder, Executive Leader and Professor
IST, LLC
Auricular Bioelectronics for Medicine and Augmented Human-Machine Cognition
Abstract
Headphones are often seen as an extension of our personal space. They are deeply connected to our human experiences, emotions, internal thoughts, and external communications. Their prevalence and utility across society surpasses many other wearable electronics. Since the ear also provides good access to biological signals encoding vital functions, health, and brain activity, the personal electronics industry has been integrating various electrical, optical, and MEMS based sensors into headphones. Simultaneously, the neuromodulation industry has been focused on interfacing hardware and electrodes with the body to control nervous system function and brain activity. Highly scalable, noninvasive methods and devices, such as auricular vagus nerve stimulation (aVNS) targets nerve branches located on the ear. Over the past couple decades, aVNS has been demonstrated to enhance attention, learning, emotion, sleep quality, decrease inflammation, and reduce stress safely and reliably through known mechanisms of action. Given these scientific advances, we were recently contracted under a SEMI-NBMC project to engineer and manufacture a next generation aVNS system named Bolster Resilience, Adaptability, and Intelligence with Neurotechnology (BRAIN Buds). We focused on optimizing human factors and usability by integrating advanced soft bioelectronic materials for superior human-device interfacing with state-of-the-art high frequency electrical neuromodulation algorithms. We will discuss how these innovations in conductive hydrogels for auricular bioelectronics and electrical neurostimulation technologies, coupled with sensor integration for neurophysiological monitoring, are poised to drive growth in the electronics industry over the next decade. Auricular bioelectronics will see traditional headphones evolve into sophisticated closed-loop, human-computer interfaces that can enhance performance, treat diseases, and optimize cognition including human-machine interactions. As consumers increasingly look for products that blend functionality with convenience and personal expression, the industry is at the cusp of a shift where new auricular bioelectronic devices (next generation headphones) will become everyday essentials, reshaping both the personal electronics and medical device industries.
Biography
William “Jamie” Tyler, Ph.D., is a co-founder and executive leader of IST, LLC and Atara Labs, Inc. He is a Professor of Biomedical Engineering and Neuroengineering at the University of Alabama at Birmingham and UAB Heersink School of Medicine. His research focuses on vagus nerve physiology, brain plasticity, and neuromodulation. Dr. Tyler has received several awards including a DARPA Young Faculty Award and McKnight Foundation Technological Innovation Award, among others, for his pioneering contributions to neuromodulation by focused ultrasound. He has led research laboratories funded by DARPA, the Army Research Office, Air Force Research Laboratories, NIH, and the NSF at his current and prior companies, as well as institutions where has been a faculty member including Arizona State University, Virginia Tech, and UAB. Dr. Tyler has played a foundational role in the development of noninvasive neuromodulation devices for the US Department of Defense and the wider public. He serves as a scientific advisor to various entities, contributing his expertise to the advancement of neuromodulation, cognitive performance, and brain health. Dr. Tyler has authored numerous influential publications as a highly cited leader in his field and holds over 50 issued and pending patents globally on neuromodulation methods and devices.